Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) usually progress toward severe loss of vision or blindness, if not aggressively treated. The aim of this study is to evaluate the efficacy of Pulse Cyclophosphamide (PCP) in a cohort study. Methods: This study includes all patients treated with PCP from 1986 to 1998, for active PU and or RV. PCP was administered as Ig cvclophosphamide/m2/body surface, once per month. Prednisolone was given ...
Abstract: The objective of this study was to compare the clinical manifestations of scleroderma(Scl) and overlap syndrome(Scl/PM). Seventy four patients with thirty five months symptoms duration of scleroderma (sixty five women, nine men) and fifteen with thirty two months symptoms duration of overlap (nine women , six men) were studied over a period of 8 years. The mean age at the disease onset was 31.8 years in Scl and 31.6 years ...
Abstract: INTRODUCTION: BD has been reported to be associated with ankylosing .spondylitis (AS) in many cases. We observed spondyloarthropathy (SpA) in our Behcet's patients more than in the normal population of Iran which is 0.18% (p
Abstract: Introduction: Vascular involvement, as a hallmark of Behcet’s disease (BD), involves arteries and veins of all size and may be a poor prognostic sign. Like the other manifestations of the disease, its prevalence varies widely according to the reports from different parts of the world (7.7 to 60%). The difference may be due to ethic variation or environmental factors. The aim of this study is to find the characteristics of ...
Abstract: Introduction: Ocular lesions are the leading cause of morbidity in Behcet’s disease (BD). Many factors contribute to the loss of vision in BD, as uveitis, retinal vasculitis, and their secondary complications such as cataract, hemorrhage, vessel necrosis, neovascularization, optic atrophy, etc. The purpose of this study was to determine the impact of retinal vasculitis on the evaluation of ocular Behcet’s (OB) and its outcome after an early or late treatment. Materials & ...
Abstract: Behcet's Disease (BD) is classified among the Vasculitides. It is characterized by mucocutaneous and ophthalmologic manifestations and seen mostly in the Northern Hemisphere and in countries along the silk road. The characteristics of BD are presented here in a nation wide analysis of 3443 patients in Iran over a 21 year period. There was a slight male preponderance M.F ratio 1.4:1 (53.3% male/46.7% female). The mean age of onset was ...
Abstract: Introduction: We reported last year, during the ACR annual meeting, the result of different treatment modalities for ocular lesions of BD in 856 patients. We showed that pulse cyclophosphamide (PCP), low dose pulse cyclophosphamide (LDP), oral cyclophosphamide (OCP), weakly methotrexate (MTX), chloambucil (CHL), and cyclosparine A (CYA) had all the same efficacy. The percentage of the eyes aggravated (visual acuity) despite the treatment was: For PCP: 21%, LDP: 22%, OCP: ...
Abstract: AIM: The aim of this study was to assess the demography of Polymyositis in Iran. Methods: In the past 20 years, we had seen 124 patients in Rheumatology Research Center. All patients were classified by the American College of Rheumatology classification criteria. Ninety five items were checked for every patient. All patients were followed regularly and the data were updated at each visit. Results: Seventy one patients were female. The female to ...
Abstract: Aim: The aim of this study was to assess the demography of polymyositis in Iranian children. Methods: 47 children classified by the ACR Criteria as having polymyositis were studied. 95 items were checked for every patient. They were followed regularly and the data were updated at each visit. Results: Thirty patients were female (64%). The acute presentation of the disease was seen in 10%. The manifestations at the onset of ...
Abstract: Aim: The aim of this study was to determine the clinical and the laboratory features of scleroderma in Iranian patients. Methods: This is a prospective study done on 350 patients from 1975 to 1995. The diagnosis of scleroderma was based on the clinical and the skin biopsy. One hundred clinical and laboratory data were completed for every patients . Results: The mean age was 29.7 years with a standard deviation (SD) of ...